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No clinically relevant interactions have been found in studies with a number of drugs that are known for their interaction potential (simvastatin, warfarin, digoxin, and oral contraceptives). Nonetheless, since albiglutide slows gastric emptying, it could conceivably increase absorption of other drugs if taken at the same time.
In drug development and medical device development [1] the Investigator's Brochure (IB) is a comprehensive document summarizing the body of information about an investigational product ("IP" or "study drug") obtained during a drug trial. The IB is a document of critical importance throughout the drug development process and is updated with new ...
An orexigenic, or appetite stimulant, is a drug, hormone, or compound that increases appetite and may induce hyperphagia.This can be a medication or a naturally occurring neuropeptide hormone, such as ghrelin, orexin or neuropeptide Y, [1] [2] which increases hunger and therefore enhances food consumption.
Drugs like Ozempic and Wegovy were already off to fast starts because of their ability to help treat Type 2 diabetes and improve weight loss for millions of Americans. But a new study suggests ...
When two drugs affect each other, it is a drug–drug interaction (DDI). The risk of a DDI increases with the number of drugs used. [1] A large share of elderly people regularly use five or more medications or supplements, with a significant risk of side-effects from drug–drug interactions. [2] Drug interactions can be of three kinds:
[9] [27] However, another study found that phentermine was a weak human serotonin 5-HT 2C receptor partial agonist (EC 50 Tooltip half-maximal effective concentration = 1,394 nM, V max = 66%). [27] In accordance with its lack of serotonin release and serotonin 5-HT 2B receptor agonism, phentermine appears to show no risk of primary pulmonary ...
In March 2023, a Novo Nordisk official said, based on a randomized, double-blind study (NCT03548935 [107]) funded by the company, that patients using semaglutide to lose weight regained two-thirds of their original weight loss one year (52 weeks) after discontinuing use of the drug. After two years (120 weeks), the patients retained roughly one ...
An OTC drug will help patients get treatment more quickly. Dr. Pearlman says it can often take months to get an appointment with a healthcare provider who can prescribe the medications commonly ...