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In hematology, red cell agglutination or autoagglutination is a phenomenon in which red blood cells clump together, forming aggregates. It is caused by the surface of the red cells being coated with antibodies .
This image explains agglutination in the blood. Agglutination is the clumping of particles. The word agglutination comes from the Latin agglutinare (glueing to).. Agglutination is a reaction in which particles (as red blood cells or bacteria) suspended in a liquid collect into clumps usually as a response to a specific antibody.
Rouleaux formation on wet smear. Rouleaux (singular is rouleau) are stacks or aggregations of red blood cells (RBCs) that form because of the unique discoid shape of the cells in vertebrates.
The direct and indirect Coombs tests, also known as antiglobulin test (AGT), are blood tests used in immunohematology.The direct Coombs test detects antibodies that are stuck to the surface of the red blood cells. [1]
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Secondary cold agglutinin syndrome occurs when autoantibodies bind to red blood cells, rendering them subject to attack by the complement system. [17] It is a result of an underlying condition potentially associated with either monoclonal cold-reacting autoantibodies or polyclonal cold-reacting autoantibodies [16] predominantly caused by infection or lymphoproliferative disorders. [16]
Whoopi Goldberg and “The View” co-hosts came to Travis Kelce’s defense ahead of Super Bowl LIX, where the Kansas City Chiefs tight end will be facing off against the Philadelphia Eagles.