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This activation can lead to symptoms of hyperandrogenism such as acne, hirsutism, polycystic ovarian syndrome, or prostate enlargement. In the canonical pathway, dihydrotestosterone is directly synthesized from testosterone by the enzyme 5α-reductase , primarily in tissues like the prostate gland , hair follicles , and skin.
Ovarian tissue banking – Ovarian tissue is frozen after oophorectomy. Even after long-term androgen therapy, ovaries usually retain usable follicles. Eventual use of frozen ovaries will require replantation into the transgender man for stimulation and harvest, but may eventually be possible in a lab as techniques for tissue culture improve.
These symptoms should be temporary and resolve within six weeks. [10] Follow-up visits with a gynecologist is recommended six-weeks following hysterectomy. Follow-up care for male-identifying patients with uterus should still see a gynecologist for a check-up at least every three years.
Right, Habitus after 3.5 years of androgen treatment. [17] Partial androgen insensitivity syndrome is diagnosed when the degree of androgen insensitivity in an individual with a 46,XY karyotype is great enough to partially prevent the masculinization of the genitalia, but is not great enough to completely prevent genital masculinization.
The symptoms of an enlarged prostate can include frequent urination and needing to get up many times in the night to pee. A man might have trouble getting started in the bathroom or dribbling when ...
The prostate, like the external male genitalia, cannot masculinize in the absence of androgen receptor function, and thus remains in the female form. [ 18 ] [ 36 ] [ 37 ] [ 38 ] The Müllerian system typically regresses the same way it does in unaffected male fetuses due to anti-Müllerian hormone originating from the Sertoli cells of the ...