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Serotonin (/ ˌ s ɛr ə ˈ t oʊ n ɪ n, ˌ s ɪər ə-/) [6] [7] [8] or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter.Its biological function is complex, touching on diverse functions including mood, cognition, reward, learning, memory, and numerous physiological processes such as vomiting and vasoconstriction.
Bufotenin acts as a potent and non-selective serotonin receptor agonist, including of the serotonin 5-HT 1A, 5-HT 2A, 5-HT 2C, and 5-HT 3 receptors, among others. [13] [6] [8] [14] It also acts as a potent and specific serotonin releasing agent. [14] The compound is more hydrophilic than other related tryptamines and consequently is more ...
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DMT inhibited SERT-mediated serotonin uptake into platelets at an average concentration of 4.00 ± 0.70 μmol/L and VMAT2-mediated serotonin uptake at an average concentration of 93 ± 6.8 μmol/L. [158] In addition, DMT is a potent serotonin releasing agent with an EC 50 Tooltip half-maximal effective concentration value of 81 to 114 nM. [142 ...
This tattoo incorporates a sun and a yin-yang symbol into the semicolon. A yin-yang signifies the complementary forces that make up life on Earth ( 7 ). Image credits: @tatynpobkatattoostudio
SP initiates expression of almost all known immunological chemical messengers . [20] [21] [22] Also, most of the cytokines, in turn, induce SP and the NK1 receptor. [23] [24] SP is particularly excitatory to cell growth and multiplication, [25] via usual, [26] as well as oncogenic drivers. [27] SP is a trigger for nausea and emesis. [28]
Serotonin Is Released. Another part of this sexy equation is serotonin—a neurotransmitter and hormone, commonly referred to as the “happy chemical,” that plays a role in regulating mood. As ...
Tryptamine is known to act as a serotonin receptor agonist, although its potency is limited by rapid inactivation by monoamine oxidases. [5] [6] [14] [31] [32] It has specifically been found to act as a full agonist of the serotonin 5-HT 2A receptor (EC 50 Tooltip half-maximal effective concentration = 7.36 ± 0.56 nM; E max = 104 ± 4%). [6]