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Cetuximab, sold under the brand name Erbitux, is an epidermal growth factor receptor (EGFR) inhibitor medication used for the treatment of metastatic colorectal cancer and head and neck cancer. [2] Cetuximab is a chimeric (mouse/human) monoclonal antibody given by intravenous infusion .
Routine use of colonoscopy screening varies globally. In the US, colonoscopy is a commonly recommended and widely utilized screening method for colorectal cancer, often beginning at age 45 or 50, depending on risk factors and guidelines from organizations like the American Cancer Society. [9] However, screening practices differ worldwide.
Traditionally, colonoscopy prep involves drinking a large amount of liquids (an oral laxative formula) to help you clean out your colon. Now, there are other options that help you achieve the same ...
A score of 4 is given if the bowel preparation is inadequate, meaning that stool obscures the mucosa despite major washing/suctioning. The total score is calculated by adding up all 3 scores. The scale has a range from 0 (perfect) to 14 (solid stool in each section and lots of fluid, i.e., a completely unprepared colon).
In drug development and medical device development [1] the Investigator's Brochure (IB) is a comprehensive document summarizing the body of information about an investigational product ("IP" or "study drug") obtained during a drug trial.
Another class of drugs used in the second line setting are epidermal growth factor receptor inhibitors, of which the three FDA approved ones are aflibercept, cetuximab and panitumumab. [149] [150] The primary difference in the approach to low-stage rectal cancer is the incorporation of radiation therapy.
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