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Post-treatment monitoring Osteopontin (OPN) is a promising tool for monitoring praziquantel efficacy and post-treatment fibrosis regression as (OPN) expression is modulated by S. mansoni egg antigens and its levels correlate with the severity of schistosomiasis fibrosis and portal hypertension in mice and humans. Praziquantel pharmacotherapy ...
A schistosomicide is a drug used to combat schistosomiasis. [1] List. Examples listed in MeSH include: [2] amoscanate; arteether; artemether; chloroxylenol; hycanthone;
Oxamniquine, sold under the brand name Vansil among others, is a medication used to treat schistosomiasis due to Schistosoma mansoni. [1] Praziquantel, however, is often the preferred treatment. [2] It is given by mouth and used as a single dose. [2] Common side effects include sleepiness, headache, nausea, diarrhea, and reddish urine. [1]
Schistosomiasis caused by trematodes of the genus Schistosoma: [13] As of 2005, praziquantel is the primary treatment for human schistosomiasis, for which it is usually effective in a single dose. [14] Clonorchiasis brought on by the Chinese liver fluke Clonorchis sinensis [15]
Schistosomiasis life cycle. Source: CDC [citation needed] A Schistosomiasis vaccine is a vaccine against Schistosomiasis (also known as bilharzia, bilharziosis or snail fever), a parasitic disease caused by several species of fluke of the genus Schistosoma. No effective vaccine for the disease exists yet.
As of 2021, 251.4 million people worldwide are having schistosomiasis due to different species of Schistosoma. [1] More than 75 million people were given medical treatment. [1] S. mansoni is the major species causing an annual death of about 130,000. [66]
Schistosoma japonicum is an important parasite and one of the major infectious agents of schistosomiasis.This parasite has a very wide host range, infecting at least 31 species of wild mammals, including nine carnivores, 16 rodents, one primate (human), two insectivores and three artiodactyls and therefore it can be considered a true zoonosis.
The treatment of schistosomiasis involves the use of anthelmintic medications, such as praziquantel or oxamniquine, to kill the adult worms. In addition, supportive care, such as rehydration and nutritional support, may be necessary for individuals with severe symptoms.