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Palmitoyl pentapeptide-4 (palmitoyl pentapeptide-3 before 2006) is a matrikine used in anti-wrinkle cosmetics. It was launched in 2000 as an active ingredient for the personal care industry under the trade name Matrixyl by the Spanish cosmetic active ingredient manufacturer Sederma SAS.
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Formulated with polypeptide Matrixyl®️ Synthe'6®️ and plumping hyaluronic acid, this peptide serum works to enhance collagen production and reduce the appearance of wrinkles and fine lines.
Both in vitro (outside a living organism) and in vivo (using a living organism) tests have been carried out, but no double-blind anti-wrinkle studies are available.. In a 2012 double-blind, placebo-controlled trial investigating treatment of blepharospasm (abnormal contraction or twitch of the eyelid), botulinum toxin injections with subsequent acetyl hexapeptide-3 treatment were compared to ...
In the United States, anti-aging products are commonly marketed with false health claims, and are deemed to be among various scams on consumers. [3] [4] Since 2007, the US Food and Drug Administration (FDA) has issued dozens of warning letters to manufacturers of skin care products with false marketing – including supposed anti-aging effects – about the benefits of such products, which are ...
Kleem Organics under-eye cream uses dermatologist-loved ingredients such as caffeine, matrixyl 3000, plant stem cells and collagen to bring hydration, smoothness, brightness and tightness to the ...