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  2. Metachromatic leukodystrophy - Wikipedia

    en.wikipedia.org/wiki/Metachromatic_leukodystrophy

    The incidence of metachromatic leukodystrophy is estimated to occur in 1 in 40,000 to 1 in 160,000 individuals worldwide. [13] There is a much higher incidence in certain genetically isolated populations, such as 1 in 75 in Habbanites (a small group of Jews who immigrated to Israel from southern Arabia), 1 in 2,500 in the western portion of the ...

  3. Metastasis - Wikipedia

    en.wikipedia.org/wiki/Metastasis

    This means that if breast cancer metastasizes to the lungs, the secondary tumor is made up of abnormal breast cells, not of abnormal lung cells. The tumor in the lung is then called metastatic breast cancer, not lung cancer. Metastasis is a key element in cancer staging systems such as the TNM staging system, where it

  4. Small-cell carcinoma - Wikipedia

    en.wikipedia.org/wiki/Small-cell_carcinoma

    Small-cell lung carcinoma (SCLC) has long been divided into two clinicopathological stages, termed limited stage (LS) and extensive stage (ES). [8] The stage is generally determined by the presence or absence of metastases, whether or not the tumor appears limited to the thorax, and whether or not the entire tumor burden within the chest can feasibly be encompassed within a single radiotherapy ...

  5. Adjuvant Libtayo® (cemiplimab) Significantly Improves Disease ...

    lite.aol.com/tech/story/0022/20250113/9330581.htm

    LIBTAYO may be used alone as your first treatment when your lung cancer has not spread outside your chest (locally advanced lung cancer) and you cannot have surgery or chemotherapy with radiation, or your lung cancer has spread to other areas of your body (metastatic lung cancer), and your tumor tests positive for high “PD-L1,” and your ...

  6. MDA-MB231 - Wikipedia

    en.wikipedia.org/wiki/MDA-MB231

    MDA-MB-231 cells were derived from a pleural effusion due to an adenocarcinoma originating in a 51-year-old caucasian female. [2] The cell line is triple negative, meaning it lacks oestrogen receptors, progesterone receptors, and HER2 (human epidermal growth factor receptor 2) amplification which many current treatment options rely on making it difficult to cure.

  7. Lung cancer - Wikipedia

    en.wikipedia.org/wiki/Lung_cancer

    Lung cancer, also known as lung carcinoma, is a malignant tumor that begins in the lung. Lung cancer is caused by genetic damage to the DNA of cells in the airways, often caused by cigarette smoking or inhaling damaging chemicals. Damaged airway cells gain the ability to multiply unchecked, causing the growth of a tumor.

  8. Treatment of lung cancer - Wikipedia

    en.wikipedia.org/wiki/Treatment_of_lung_cancer

    In a 2010 study of patients with metastatic non–small-cell lung cancer, "early palliative care led to significant improvements in both quality of life and mood. As compared with patients receiving standard care, patients receiving early palliative care had less aggressive care at the end of life but longer survival" which was increased by ...

  9. Lewis lung carcinoma - Wikipedia

    en.wikipedia.org/wiki/Lewis_lung_carcinoma

    Generally, Lewis lung carcinoma is highly metastatic in immunocompetent mice. [4] If subcutaneously injected into mice, it is known to avidly metastasize to the lung. In fact, a 1996 study found that the carcinoma predominantly metastasized into the lungs after tail vein injections. [5]