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Staphylococcus epidermidis is a Gram-positive bacterium, and one of over 40 species belonging to the genus Staphylococcus. [1] It is part of the normal human microbiota , typically the skin microbiota , and less commonly the mucosal microbiota and also found in marine sponges.
S. epidermidis, a coagulase-negative staphylococcus species, is a commensal of the skin, but can cause severe infections in immune-suppressed patients and those with central venous catheters. S. saprophyticus , another coagulase -negative species that is part of the normal vaginal flora , is predominantly implicated in uncomplicated lower ...
Staphylococcus epidermidis and Staphylococcus aureus were thought from cultural based research to be dominant. However 16S ribosomal RNA research finds that while common, these species make up only 5% of skin bacteria. However, skin variety provides a rich and diverse habitat for bacteria.
Microorganisms like Staphylococcus epidermidis colonize the skin surface. The density of skin flora depends on region of the skin. The density of skin flora depends on region of the skin. The disinfected skin surface gets recolonized from bacteria residing in the deeper areas of the hair follicle, gut and urogenital openings.
SSSS is a clinical diagnosis. This is sometimes confirmed by isolation of S. aureus from blood, mucous membranes, or skin biopsy; however, these are often negative. Skin biopsy may show separation of the superficial layer of the epidermis (intraepidermal separation), differentiating SSSS from TEN, wherein the separation occurs at the dermo-epidermal junction (subepidermal separation).
S. epidermidis, a coagulase-negative species, is a commensal of the skin, but can cause severe infections in immunosuppressed patients and those with central venous catheters. S. saprophyticus , another coagulase-negative species that is part of the normal vaginal flora , is predominantly implicated in genitourinary tract infections in sexually ...
Miliaria occurs when sweat glands become clogged due to dead skin cells or bacteria such as Staphylococcus epidermidis, [9] a common bacterium that occurs on the skin, which is also associated with acne. The trapped sweat leads to irritation (prickling), itching, and a rash of very small blisters, usually in a localized area of the skin.
Skin immunity is a property of skin that allows it to resist infections from pathogens. In addition to providing a passive physical barrier against infection, the skin also contains elements of the innate and adaptive immune systems which allows it to actively fight infections. Hence the skin provides defense in depth against infection.