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Somnifacient (from Latin somnus, sleep [1]), also known as sedatives or sleeping pills, is a class of medications that induces sleep. It is mainly used for treatment of insomnia. Examples of somnifacients include benzodiazepines, barbiturates and antihistamines. Around 2-6% of adults with insomnia use somnifacients to aid sleep. [2]
Lemborexant is used in the treatment of insomnia in adults. [3]A major systematic review and network meta-analysis of medications for the treatment of insomnia published in 2022 found that lemborexant had an effect size (standardized mean difference (SMD)) against placebo for treatment of insomnia at 4 weeks of 0.36 (95% CI Tooltip confidence interval 0.08 to 0.63) and at 3 months of 0.41 (95% ...
Sedation is the side effect people taking lorazepam most frequently report. In a group of around 3,500 people treated for anxiety, the most common side effects complained of from lorazepam were sedation (15.9%), dizziness (6.9%), weakness (4.2%), and unsteadiness (3.4%). Side effects such as sedation and unsteadiness increased with age. [61]
Sleep Disturbances. Insomnia and a general reduction in sleep quality are both common side effects of SSRIs and other antidepressants. A 2017 review of research literature published in the journal ...
According to the Anxiety and Depression Association of America (ADAA), 6.8 million adults have GAD. Other anxiety disorders include obsessive-compulsive disorder, panic disorder, post-traumatic ...
A role for medication. Clinical practice guidelines from the American Academy of Sleep Medicine consistently recommend CBT-I as the first-line treatment for chronic insomnia. “There are multiple ...
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