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As of 2023, PBMs managed pharmacy benefits for 275 million Americans and the three largest PBMs in the US, CVS Caremark, Cigna Express Scripts, and UnitedHealth Group’s Optum Rx, make up about 80% of the market share covering about 270 million people [4] [5] with a market of almost $600 billion in 2024.
The number of people with depression has reached new highs—and so has antidepressant use. As Americans are increasingly reaching for pharmaceutical solutions for depression—about one in eight ...
Antidepressants could increase the risk of suicidal thoughts and behavior in people with depression under the age of 25. In 2004, the U.S. Food and Drug Administration along with the Neuro-Psychopharmacologic Advisory Committee and the Anti-Infective Drugs Advisory Committee, concluded that there was a causal link between newer antidepressants and pediatric suicidality. [7]
With more chronic forms of depression, the most effective treatment is often considered to be a combination of medication and psychotherapy. [6] [9] Psychotherapy is the treatment of choice in people under 18. [8] A meta-analysis examined the effectiveness of psychotherapy for depression across ages from younger than 13 years to older than 75 ...
Approximately 15–50% of people who suddenly stop an antidepressant develop antidepressant discontinuation syndrome. [7] [2] [3] [4] The condition is generally not serious, [2] though about half of people with symptoms describe them as severe. [4] Many restart antidepressants due to the severity of the symptoms. [4]
The NFL playoff schedule is about to be set, with the wild-card dates and times for every matchup to be revealed during Week 18.
The personality was indicative of depression history, but self-criticism in an interaction with immature dependence was able to predict future episodes of depression as well. In a sample of people who either currently have depression or are in remission from a depressive episode, individuals reported both higher levels of self-criticism and ...
The Colorado college football coach served up another reminder that he will intervene if the wrong NFL team drafts his quarterback son in April.