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Bisacodyl is an organic compound that is used as a stimulant laxative drug. It works directly on the colon to produce a bowel movement. It is typically prescribed for relief of episodic and chronic constipation and for the management of neurogenic bowel dysfunction, as well as part of bowel preparation before medical examinations, such as for a colonoscopy.
Traditionally, colonoscopy prep involves drinking a large amount of liquids (an oral laxative formula) to help you clean out your colon. Now, there are other options that help you achieve the same ...
Sodium picosulfate is a prodrug. [5] It has no significant direct physiological effect on the intestine; however, it is metabolised by gut bacteria into the active compound 4,4'-dihydroxydiphenyl-(2-pyridyl)methane (DPM, BHPM).
Colonoscopy (/ ˌ k ɒ l ə ˈ n ɒ s k ə p i /) or coloscopy (/ k ə ˈ l ɒ s k ə p i /) [1] is a medical procedure involving the endoscopic examination of the large bowel (colon) and the distal portion of the small bowel. This examination is performed using either a CCD camera or a fiber optic camera, which is mounted on a flexible tube ...
A single-use rotatable endoclip in packaging An endoclip is a metallic mechanical device used in endoscopy in order to close two mucosal surfaces without the need for surgery and suturing . Its function is similar to a suture in gross surgical applications, as it is used to join together two disjointed surfaces, but, can be applied through the ...
The scale assesses three components of the large intestine: (1) the rectosigmoid colon, (2) the mid colon and (3) the right colon. A maximum score of 4 is used for each section of the large intestine. A score of 0 is given if the bowel preparation is excellent, meaning the mucosal detail is visible, there is no fluid and almost no stool.
Macrogol came into use as a bowel prep in 1980 and was approved for medical use in the United States in 1999. [ 10 ] [ 11 ] [ 12 ] It is available as a generic medication and over the counter . [ 3 ] [ 13 ] In 2022, it was the 209th most commonly prescribed medication in the United States, with more than 1 million prescriptions.
Prolonged use of stimulant laxatives can create drug dependence by damaging the colon's haustral folds, making users less able to move feces through their colon on their own. A study of patients with chronic constipation found that 28% of chronic stimulant laxative users lost haustral folds over the course of one year, while none of the control ...