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As globus sensation is a symptom, a diagnosis of globus pharyngis is typically a diagnosis of exclusion.If globus sensation is presenting with other symptoms such as pain, swallowing disorders such as aspiration or regurgitation (dysphagia), weight loss, or voice change, [10] an organic cause needs to be investigated, typically with endoscopy.
However, when present, symptoms may include difficulty swallowing , pain while swallowing (odynophagia), cough or globus sensation. [1] Whether esophageal inlet patches may cause other symptoms, such as chronic cough or laryngitis, is unclear. [1] Occasionally, esophageal inlet patches may be seen during a barium esophagram. [3]
Dysphagia is distinguished from other symptoms including odynophagia, which is defined as painful swallowing, [8] and globus, which is the sensation of a lump in the throat. A person can have dysphagia without odynophagia (dysfunction without pain), odynophagia without dysphagia (pain without dysfunction) or both together.
Eagle syndrome (also termed stylohyoid syndrome, [1] styloid syndrome, [2] stylalgia, [3] styloid-stylohyoid syndrome, [2] or styloid–carotid artery syndrome) [4] is an uncommon condition commonly characterized but not limited to sudden, sharp nerve-like pain in the jaw bone and joint, back of the throat, and base of the tongue, triggered by swallowing, moving the jaw, or turning the neck. [1]
Pseudodysphagia, in its severe form, is the irrational fear of swallowing or, in its minor form, of choking. The symptoms are psychosomatic, so while the sensation of difficult swallowing feels authentic to the individual, it is not based on a real physical symptom.
A patient and doctor discuss congenital insensitivity to pain. For people with this disorder, cognition and sensation are otherwise normal; for instance, patients can still feel discriminative touch (though not always temperature [3]), and there are generally no detectable physical abnormalities.
Of all the circuits, the motor circuit is the most studied due its importance to motor disorders. The direct pathway of the motor circuit is one in which projections from the cortex travel to the putamen directly to the internal segment of the globus pallidus (GPi also known as GP-Medial) or the substantia nigra, pars reticulata (SNr) and are then directed toward the ventral anterior nucleus ...
The external globus pallidus is the segment of the globus pallidus that is relatively further (lateral) from the midline of the brain. The GPe is predominantly composed of inhibitory GABAergic neurons that project axons to the subthalamic nucleus (in the diencephalon), the striatum, internal globus pallidus (GPi) and substantia nigra pars ...