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  2. Pathogen-associated molecular pattern - Wikipedia

    en.wikipedia.org/wiki/Pathogen-associated...

    Pathogen-associated molecular patterns (PAMPs) are small molecular motifs conserved within a class of microbes, but not present in the host. [1] They are recognized by toll-like receptors (TLRs) and other pattern recognition receptors (PRRs) in both plants and animals. [ 2 ]

  3. Danger model - Wikipedia

    en.wikipedia.org/wiki/Danger_model

    Function of T helper cells: Antigen-presenting cells present antigens on their Class II MHC molecules . Helper T cells recognize these by expressing the CD4 co-receptor . The activation of a resting helper T cell causes it to release cytokines and other signals (green arrows) that stimulate the activity of macrophages , killer T cells , and B ...

  4. Immunological memory - Wikipedia

    en.wikipedia.org/wiki/Immunological_memory

    The adaptive immune system and antigen-specific receptor generation (TCR, antibodies) are responsible for adaptive immune memory. [citation needed] After the inflammatory immune response to danger-associated antigen, some of the antigen-specific T cells and B cells persist in the body and become long-living memory T and B cells. After the ...

  5. Pattern recognition receptor - Wikipedia

    en.wikipedia.org/wiki/Pattern_recognition_receptor

    The microbe-specific molecules that are recognized by a given PRR are called pathogen-associated molecular patterns (PAMPs) and include bacterial carbohydrates (such as lipopolysaccharide or LPS, mannose), nucleic acids (such as bacterial or viral DNA or RNA), bacterial peptides (flagellin, microtubule elongation factors), peptidoglycans and ...

  6. Damage-associated molecular pattern - Wikipedia

    en.wikipedia.org/wiki/Damage-associated...

    Thus, free radical-mediated reperfusion injury was seen to contribute to the process of innate and subsequent adaptive immune responses. [ 9 ] The second study [ 10 ] suggested the possibility that the immune system detected "danger", through a series of what is now called damage-associated molecular pattern molecules (DAMPs), working in ...

  7. Antibody opsonization - Wikipedia

    en.wikipedia.org/wiki/Antibody_opsonization

    1) Antibodies (A) and pathogens (B) circular in the blood. 2) The antibodies bind to pathogens with complementary antigen sequences, engaging in opsonization (2a), neutralisation (2b), and agglutination (2c). 3) A phagocyte (C) approaches the pathogen, and Fc region (D) of the antibody binds to one of the Fc receptors (E) on the phagocyte.

  8. NYT ‘Connections’ Hints and Answers Today, Monday, January 13

    www.aol.com/nyt-connections-hints-answers-today...

    If you've been having trouble with any of the connections or words in Monday's puzzle, you're not alone and these hints should definitely help you out. Plus, I'll reveal the answers further down ...

  9. CpG oligodeoxynucleotide - Wikipedia

    en.wikipedia.org/wiki/CpG_Oligodeoxynucleotide

    Since 1893, it has been recognized that Coley's toxin, a mixture of bacterial cell lysate, has immunostimulatory properties that could reduce the progression of some carcinomas, [4] but it was not until 1983 that Tokunaga et al. specifically identified bacterial DNA as the underlying component of the lysate that elicited the response. [5]