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Severe side effects may include low blood pressure with standing, an irregular heart beat, and priapism. [2] [3] It is a selective α 1-adrenergic blocker in the quinazoline class of compounds. [2] Doxazosin was patented in 1977 and came into medical use in 1988. [4] It is available as a generic medication. [3]
At low doses, below 25 mg, doxepin is a pure antihistamine and has more of a sedative effect. [53] At antidepressant doses of above 75 mg, doxepin is more stimulating with antiadrenergic, antiserotonergic, and anticholinergic effects, and these activities contribute to its side effects. [54] [53] [12]
Terazosin, tamsulosin and doxazosin are prime drug for BPH because they have a long half-life and modified release formulation. Tamsulosin is primarily used because it doesn't affect the blood pressure and the side effects of vasodilation is minimum. [44] [45] [2]
Common side effects include movement problems, sleepiness, dry mouth, low blood pressure upon standing, and increased weight. [6] Serious side effects may include the potentially permanent movement disorder tardive dyskinesia , neuroleptic malignant syndrome , severe lowering of the seizure threshold , and low white blood cell levels . [ 6 ]
Side effects associated with phentolamine include headache, flushing, and nasal congestion. [23] Benign prostate hyperplasia, a disease in which urinary retention becomes an issue. Alpha-1 blockers can be used, but it can result in side effects such as increased urination and retrograde ejaculation.
Side effects that are common (based on its pharmacology or the frequency of these side effects with related agents) appear with a * superscript whereas the serious side effects are in bold. Doxepin is licensed to be used in much smaller doses (viz., 3mg and 6 mg) in some countries, the side-effects profile of which may differ from this list.
Like any medication, side effects of Viagra may come with its many benefits. Still, Viagra is safe when used as directed. Viagra may cause common side effects, including: Flushing.
Syncope occurs in approximately 1% of patients given an initial dose of 2 mg prazosin or greater. This adverse effect is self-limiting and in most cases does not recur after the initial period of therapy or during subsequent dose titration. [3] The alpha blocker prazosin (Minipress) is most notorious for producing a first dose phenomenon.