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  2. Doxycycline - Wikipedia

    en.wikipedia.org/wiki/Doxycycline

    Doxycycline blocks protein production in apicoplast (an organelle) of P. falciparum—such blocking leads to two main effects: it disrupts the parasite's ability to produce fatty acids, which are essential for its growth, and it impairs the production of heme, a cofactor.

  3. Apicoplast - Wikipedia

    en.wikipedia.org/wiki/Apicoplast

    An apicoplast is a derived non-photosynthetic plastid found in most Apicomplexa, including Toxoplasma gondii, and Plasmodium falciparum and other Plasmodium spp. ...

  4. Tetracycline antibiotics - Wikipedia

    en.wikipedia.org/wiki/Tetracycline_antibiotics

    Doxycycline is also used as a prophylactic treatment for infection by Bacillus anthracis and is effective against Yersinia pestis, the infectious agent of bubonic plague. It is also used for malaria treatment and prophylaxis, as well as treating elephantitis filariasis . [ 10 ]

  5. Tetracycline-controlled transcriptional activation - Wikipedia

    en.wikipedia.org/wiki/Tetracycline-controlled...

    Example of a T-REx system controlling the expression of shRNA. Tetracycline-controlled transcriptional activation is a method of inducible gene expression where transcription is reversibly turned on or off in the presence of the antibiotic tetracycline or one of its derivatives (e.g. doxycycline).

  6. Sulfadoxine/pyrimethamine - Wikipedia

    en.wikipedia.org/wiki/Sulfadoxine/pyrimethamine

    It is approved in the United States as a treatment and preventive measure against malaria. [6] The combination is considered to be more effective in treating malaria caused by Plasmodium falciparum than that caused by P. vivax, for which chloroquine is considered more effective, though in the absence of a species-specific diagnosis, the sulfadoxine-pyrimethamine combination may be indicated. [7]

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  8. AOL Mail for Verizon Customers - AOL Help

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  9. Alleged racist rants of Yellowstone park shooter uncovered in ...

    www.aol.com/alleged-racist-rants-yellowstone...

    In a new court filing, federal prosecutors allege the suspect who took a hostage and got into a shootout with Yellowstone National Park rangers in July ranted that he "refuse[s] to fraternize with ...