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UniProt Archive (UniParc) is a comprehensive and non-redundant database, which contains all the protein sequences from the main, publicly available protein sequence databases. [17] Proteins may exist in several different source databases, and in multiple copies in the same database.
database of protein similarities computed using FASTA: Protein model databases Swiss-model: server and repository for protein structure models Protein model databases AAindex: database of amino acid indices, amino acid mutation matrices, and pair-wise contact potentials Protein model databases BioGRID: Samuel Lunenfeld Research Institute
In 2002, PIR – along with its international partners, the European Bioinformatics Institute and the Swiss Institute of Bioinformatics – were awarded a grant from NIH to create UniProt, a single worldwide database of protein sequence and function, by unifying the Protein Information Resource-Protein Sequence Database, Swiss-Prot, and TrEMBL ...
Originally conceived as the individual ventures of EMBL-EBI, Swiss Institute of Bioinformatics (SIB) (together maintaining Swiss-Prot and TrEMBL) and Protein Information Resource (PIR) (housing Protein Sequence Database), the increase in the global protein data generation led to their collaboration in the creation of UniProt in 2002. [16]
The UniProt database is an example of a protein sequence database. As of 2013 it contained over 40 million sequences and is growing at an exponential rate. [ 1 ] Historically, sequences were published in paper form, but as the number of sequences grew, this storage method became unsustainable.
Uniprot — the universal protein database, a central resource on protein information - PROSITE adds data to it. InterPro — a centralized database, grouping data from databases of protein families, domains and functional sites - part of the data come from PROSITE. Protein subcellular localization prediction — another example of use of PROSITE.
This is a list of major bioinformatics institutions.. National Center for Biotechnology Information (NCBI); European Bioinformatics Institute (EMBL-EBI); Australia Bioinformatics Resource (EMBL-ABR)
The single amino acid annotations were fetched from UniProt database, [7] then mapped to PDB structures following residue-level information from SIFTS database. [ 8 ] Instructions of Protein Pocket Calculation