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Nicotinamide adenine dinucleotide phosphate, abbreviated NADP [1] [2] or, in older notation, TPN (triphosphopyridine nucleotide), is a cofactor used in anabolic reactions, such as the Calvin cycle and lipid and nucleic acid syntheses, which require NADPH as a reducing agent ('hydrogen source').
A biological coenzyme that acts as an electron carrier in enzymatic reactions. NADP is a reducing agent in anabolic reactions like the Calvin cycle and lipid and nucleic acid syntheses. NADP exists in two forms: NADP+, the oxidized form, and NADPH, the reduced form.
In enzymology, a hydrogen dehydrogenase (NADP+) (EC 1.12.1.3) is an enzyme that catalyzes the chemical reaction H 2 + NADP + ⇌ {\displaystyle \rightleftharpoons } H + + NADPH Thus, the two substrates of this enzyme are H 2 and NADP + , whereas its two products are H + and NADPH .
In enzymology, an aldehyde dehydrogenase (NADP+) (EC 1.2.1.4) is an enzyme that catalyzes the chemical reaction. an aldehyde + NADP + + H 2 O an acid + NADPH + H +. The 3 substrates of this enzyme are aldehyde, NADP +, and H 2 O, whereas its 3 products are acid, NADPH, and H +.
Isocitrate dehydrogenase 1 (NADP+), soluble is an enzyme that in humans is encoded by the IDH1 gene on chromosome 2. Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which uses NAD + as the electron acceptor and the other NADP +.
In enzymology, a dihydropyrimidine dehydrogenase (NADP+) (EC 1.3.1.2) is an enzyme that catalyzes the chemical reaction. 5,6-dihydrouracil + NADP + uracil + NADPH + H +. Thus, the two substrates of this enzyme are 5,6-dihydrouracil and NADP +, whereas its 3 products are uracil, NADPH, and H +.
In enzymology, a malate dehydrogenase (NADP +) (EC 1.1.1.82) is an enzyme that catalyzes the chemical reaction (S)-malate + NADP + oxaloacetate + NADPH + H +. Thus, the two substrates of this enzyme are (S)-malate and NADP +, whereas its 3 products are oxaloacetate, NADPH, and H +.
In enzymology, an alcohol dehydrogenase [NAD(P) +] (EC 1.1.1.71) is an enzyme that catalyzes the chemical reaction. an alcohol + NAD(P) + an aldehyde + NAD(P)H + H + The 3 substrates of this enzyme are alcohol, NAD +, and NADP +, whereas its 4 products are aldehyde, NADH, NADPH, and H +.