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Lactase persistence is very high among northern Europeans, especially Irish people. Worldwide, most people are lactase non-persistent, [1] and are affected by varying degrees of lactose intolerance as adults. However, lactase persistence and lactose intolerance can overlap.
This form of lactose intolerance can occur in both infants and lactase persistent adults and is generally reversible. [29] It may be caused by acute gastroenteritis , coeliac disease , Crohn's disease , ulcerative colitis , [ 30 ] chemotherapy , intestinal parasites (such as giardia ), or other environmental causes.
Many adults are lactose intolerant because their bodies cease production of the enzyme lactase post childhood. However, mutations in the promoter region of the lactase gene (LCT) result in the continued production of lactase throughout adulthood in certain African populations, a condition known as lactase persistence. A study conducted by Sarah ...
In 2004 he led a study to show that most lactase persistent Africans did not have the same mutation causing it as Europeans. [8] In 2007, in collaboration with Joachim Burger 's group in Mainz, Germany, he showed that the genetic variant that causes lactase persistence in most Europeans (-13,910*T) was rare or absent in early farmers from ...
Lactase (EC 3.2.1.108) is an enzyme produced by many organisms and is essential to the complete digestion of whole milk.It breaks down the sugar lactose into its component parts, galactose and glucose.
The Dry January campaign was started in 2013 by Alcohol Change U.K., a charity focused on reducing alcohol harm. What are the health benefits of Dry January? While research on how quitting alcohol ...
Mayo Clinic Proceedings is a monthly peer-reviewed medical journal published by Elsevier and sponsored by the Mayo Clinic. It covers the field of general internal medicine. The journal was established in 1926 as the Proceedings of the Staff Meetings of the Mayo Clinic and obtained its current name in 1964.
Lactose can not be absorbed by the intestine and needs to be split in the small intestine into galactose and glucose by the enzyme called lactase; unabsorbed lactose can cause abdominal pain, bloating, diarrhea, gas, and nausea. [citation needed] In most mammals, production of lactase diminishes after infants are weaned from maternal milk.
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