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  2. Langerhans cell histiocytosis - Wikipedia

    en.wikipedia.org/wiki/Langerhans_cell_histiocytosis

    With multi-focal disease 60% have a chronic course, 30% achieve remission and mortality is up to 10%. [48] A full recovery can be expected for people who seek treatment and do not have more lesions at 12 and 24 months. However, 50% of children under 2 with disseminated Langerhans cell histiocytosis die of the disease.

  3. Blastic plasmacytoid dendritic cell neoplasm - Wikipedia

    en.wikipedia.org/wiki/Blastic_plasmacytoid...

    Blastic plasmacytoid dendritic cell neoplasm typically responds to chemotherapy regimens used to treat hematological malignancies. All too often, however, the disease rapidly recurs and does so in a more drug-resistant form. [5] Furthermore, the disease may occur in association with the myelodysplastic syndrome or transform to acute myeloid ...

  4. Acute lymphoblastic leukemia - Wikipedia

    en.wikipedia.org/wiki/Acute_lymphoblastic_leukemia

    Although 80 to 90% of children will have a long term complete response with treatment, [45]: 1527 it remains the leading cause of cancer-related deaths among children. [82] 85% of cases are of B-cell lineage and have an equal number of cases in both males and females. The remaining 15% of T-cell lineage have a male predominance.

  5. Embryonal rhabdomyosarcoma - Wikipedia

    en.wikipedia.org/wiki/Embryonal_rhabdomyosarcoma

    Safety concerns regarding the long term effects of chemotherapy remains a concern. Side effects of the VAC regimen include nausea, vomiting, liver damage, and immune system suppression. [36] The length and dosing of the chemotherapy is oftentimes on a case-by-case basis based on the person's stage of cancer, site of tumor and age.

  6. List of childhood diseases and disorders - Wikipedia

    en.wikipedia.org/wiki/List_of_childhood_diseases...

    The term childhood disease refers to disease that is contracted or becomes symptomatic before the age of 18 or 21 years old. Many of these diseases can also be contracted by adults. Some childhood diseases include:

  7. Tumor lysis syndrome - Wikipedia

    en.wikipedia.org/wiki/Tumor_lysis_syndrome

    Tumor lysis syndrome (TLS) is a group of metabolic abnormalities that can occur as a complication from the treatment of cancer, where large amounts of tumor cells are killed off from the treatment, releasing their contents into the bloodstream. [1]

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  9. Acute promyelocytic leukemia - Wikipedia

    en.wikipedia.org/wiki/Acute_promyelocytic_leukemia

    Acute promyelocytic leukemia is characterized by a chromosomal translocation involving the retinoic acid receptor alpha (RARA) gene on chromosome 17. [3] In 95% of cases of APL, the RARA gene on chromosome 17 is involved in a reciprocal translocation with the promyelocytic leukemia gene (PML) on chromosome 15, a translocation denoted as t(15;17)(q22;q21). [3]