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One type of antispasmodics is used for smooth muscle relaxation, especially in tubular organs of the gastrointestinal tract. The effect is to prevent spasms of the stomach, intestine or urinary bladder. Both dicyclomine and hyoscyamine are antispasmodic due to their anticholinergic action. [medical citation needed] Both of these drugs have side ...
Metamizole. Urine (96%, IV; 85%, oral), faeces (4%, IV). [4] Metamizole or dipyrone is a painkiller, spasm reliever, and fever reliever drug. It is most commonly given by mouth or by intravenous infusion. [13][11][14] It belongs to the ampyrone sulfonate family of medicines and was patented in 1922.
Drotaverine. Drotaverine (INN, also known as drotaverin) is an antispasmodic drug, used to enhance cervical dilation during childbirth and to relieve smooth muscle spasms in the gastrointestinal tract, urinary system, and gall bladder. [2][3][4][5] It is structurally related to papaverine, and is a selective inhibitor of phosphodiesterase-4 ...
Hyoscine butylbromide. Hyoscine butylbromide, also known as scopolamine butylbromide[4] and sold under the brandname Buscopan among others, [5] is an anticholinergic medication used to treat abdominal pain, esophageal spasms, bladder spasms, biliary colic, [6] and renal colic. [7][8] It is also used to improve excessive respiratory secretions ...
Baclofen, sold under the brand name Lioresal among others, is a medication used to treat muscle spasticity such as from a spinal cord injury or multiple sclerosis. [8][9] It may also be used for hiccups and muscle spasms near the end of life, [9] and off-label to treat alcohol use disorder [10][11] or opioid withdrawal symptoms. [12]
Eperisone. Eperisone (formulated as the eperisone hydrochloride salt) is an antispasmodic drug. Eperisone acts by relaxing both skeletal muscles and vascular smooth muscles, and demonstrates a variety of effects such as reduction of myotonia, improvement of circulation, and suppression of the pain reflex. The drug inhibits the vicious circle of ...
Mebeverine is an anticholinergic but its mechanism of action is not known; it appears to work directly on smooth muscle within the gastrointestinal tract and may have an anaesthetic effect, may affect calcium channels, and may affect muscarinic receptors. [2]
Donnatal is a combination medication that provides natural belladonna alkaloids in a specific fixed ratio combined with phenobarbital to provide peripheral anticholinergic / antispasmodic action and mild sedation. [1][2] Donnatal is manufactured for Concordia Pharmaceuticals by IriSys, LLC. It is available as tablets [1] and 5 mL elixir. [2]