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Death is often due to lung, gastrointestinal, or heart complications. [3] About three per 100,000 people per year develop the systemic form. [3] The condition most often begins in middle age. [1] Women are more often affected than men. [1] Scleroderma symptoms were first described in 1753 by Carlo Curzio [9] and then well documented in 1842. [10]
Systemic scleroderma, or systemic sclerosis, is an autoimmune rheumatic disease characterised by excessive production and accumulation of collagen, called fibrosis, in the skin and internal organs and by injuries to small arteries. There are two major subgroups of systemic sclerosis based on the extent of skin involvement: limited and diffuse.
Mixed connective tissue disease (MCTD) is a systemic autoimmune disease that shares characteristics with at least two other systemic autoimmune diseases, including systemic sclerosis (Ssc), systemic lupus erythematosus (SLE), polymyositis / dermatomyositis (PM/DM), and rheumatoid arthritis. [2] The idea behind the "mixed" disease is that this ...
Derek Stefureac was at work when the first symptom of multiple sclerosis hit, sharing that the diagnosis was "like a punch in the stomach" The Las Vegas resident started running as a way to quit ...
Werner syndrome patients exhibit growth retardation, short stature, premature graying of hair, alopecia (hair loss), wrinkling, prematurely aged faces with beaked noses, skin atrophy (wasting away) with scleroderma-like lesions, lipodystrophy (loss of fat tissues), abnormal fat deposition leading to thin legs and arms, and severe ulcerations around the Achilles tendon and malleoli (around ankles).
The latest data from the Texas Health and Human Services Commission on induced terminations of pregnancies (HHSC ITOP) shows that doctors in Texas performed 113 abortions to save pregnant women ...
The rare disease hardens the skin and internal organs of young women of child-bearing age causing disfigurement, and is potentially fatal. [5] In reaction to the lack of awareness of the disease in the medical community, she went on to found the Scleroderma Research Foundation in 1987, [2] an organization dedicated to finding a cure. [4]
Deaths from autoimmune disease. Deaths from musculoskeletal disorders. Deaths from sclerosis. Systemic connective tissue disorders. Mucinoses. Rare diseases. People with rare diseases. Hidden category: Commons category link from Wikidata.