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Chemistry. [edit] Melatonin, also known as N -acetyl-5-methoxytryptamine, is a substituted tryptamine and a derivative of serotonin (5-hydroxytryptamine). It is structurally related to N-acetylserotonin (normelatonin; N -acetyl-5-hydroxytryptamine), which is the chemical intermediate between serotonin and melatonin in the body.
Melatonin, an indoleamine, is a natural compound produced by various organisms, including bacteria and eukaryotes. [1] Its discovery in 1958 by Aaron B. Lerner and colleagues stemmed from the isolation of a substance from the pineal gland of cows that could induce skin lightening in common frogs.
Hypovolemia, also known as volume depletion or volume contraction, is a state of abnormally low extracellular fluid in the body. [ 1 ] This may be due to either a loss of both salt and water or a decrease in blood volume. [ 2 ][ 3 ] Hypovolemia refers to the loss of extracellular fluid and should not be confused with dehydration.
Ashwagandha is an adaptogen, an herb that helps regulate the stress hormone cortisol. It comes from a shrub that grows in Africa and Asia, but you can often buy it as a capsule, powder, or tea ...
Volume contraction. Volume contraction is a decrease in the volume of body fluid, including the dissolved substances that maintain osmotic balance (osmolytes). The loss of the water component of body fluid is specifically termed dehydration. [1]
Replacement of fluids, surgery to repair cause of bleeding. Hypovolemic shock is a form of shock caused by severe hypovolemia (insufficient blood volume or extracellular fluid in the body). [ 1 ][ 2 ] It can be caused by severe dehydration or blood loss. [ 3 ][ 2 ] Hypovolemic shock is a medical emergency; if left untreated, the insufficient ...
Melatonin receptors are G protein-coupled receptors (GPCR) which bind melatonin. [1] Three types of melatonin receptors have been cloned.The MT 1 (or Mel 1A or MTNR1A) and MT 2 (or Mel 1B or MTNR1B) receptor subtypes are present in humans and other mammals, [2] while an additional melatonin receptor subtype MT 3 (or Mel 1C or MTNR1C) has been identified in amphibia and birds. [3]
Shock is the state of insufficient blood flow to the tissues of the body as a result of problems with the circulatory system. [1][2] Initial symptoms of shock may include weakness, fast heart rate, fast breathing, sweating, anxiety, and increased thirst. [1] This may be followed by confusion, unconsciousness, or cardiac arrest, as complications ...