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  2. Aspartate transaminase - Wikipedia

    en.wikipedia.org/wiki/Aspartate_transaminase

    Aspartate transaminase (AST) or aspartate aminotransferase, also known as AspAT/ASAT/AAT or (serum) glutamic oxaloacetic transaminase (GOT, SGOT), is a pyridoxal phosphate (PLP)-dependent transaminase enzyme (EC 2.6.1.1) that was first described by Arthur Karmen and colleagues in 1954. [1][2][3] AST catalyzes the reversible transfer of an α ...

  3. Liver function tests - Wikipedia

    en.wikipedia.org/wiki/Liver_function_tests

    S.G.O.T. (ALT), S.G.P.T. (AST) Liver function tests (LFTs or LFs), also referred to as a hepatic panel, are groups of blood tests that provide information about the state of a patient's liver. [1] These tests include prothrombin time (PT/INR), activated partial thromboplastin time (aPTT), albumin, bilirubin (direct and indirect), and others.

  4. AST/ALT ratio - Wikipedia

    en.wikipedia.org/wiki/AST/ALT_ratio

    The proportion of AST to ALT in hepatocytes is about 2.5:1, but because AST is removed from serum by the liver sinusoidal cells twice as quickly (serum half-life t 1/2 = 18 hr) compared to ALT (t 1/2 = 36 hr), so the resulting serum levels of AST and ALT are about equal in healthy individuals, resulting in a normal AST/ALT ratio around 1.

  5. Alanine transaminase - Wikipedia

    en.wikipedia.org/wiki/Alanine_transaminase

    Alanine transaminase (ALT), also known as alanine aminotransferase (ALT or ALAT), formerly serum glutamate-pyruvate transaminase (GPT) or serum glutamic-pyruvic transaminase (SGPT), is a transaminase enzyme (EC 2.6.1.2) that was first characterized in the mid-1950s by Arthur Karmen and colleagues. [1] ALT is found in plasma and in various body ...

  6. Fatty liver disease - Wikipedia

    en.wikipedia.org/wiki/Fatty_liver_disease

    Fatty liver disease (FLD), also known as hepatic steatosis and steatotic liver disease (SLD), is a condition where excess fat builds up in the liver. [1] Often there are no or few symptoms. [1][2] Occasionally there may be tiredness or pain in the upper right side of the abdomen. [1] Complications may include cirrhosis, liver cancer, and ...

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    You can find instant answers on our AOL Mail help page. Should you need additional assistance we have experts available around the clock at 800-730-2563.

  8. Hy's law - Wikipedia

    en.wikipedia.org/wiki/Hy's_law

    Hy's Law cases have three components: [2] The drug causes hepatocellular injury, generally defined as an elevated ALT or AST by 3-fold or greater above the upper limit of normal. Often with aminotransferases much greater (5-10x) than the upper limit of normal. Among subjects showing such aminotransferase elevations, they also have elevation of ...

  9. Comprehensive metabolic panel - Wikipedia

    en.wikipedia.org/wiki/Comprehensive_metabolic_panel

    003468. LOINC. 24322-0, 24323-8. The comprehensive metabolic panel, or chemical screen (CMP; CPT code 80053), is a panel of 14 blood tests that serves as an initial broad medical screening tool. The CMP provides a rough check of kidney function, liver function, diabetic and parathyroid status, and electrolyte and fluid balance, but this type of ...