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An attenuated vaccine (or a live attenuated vaccine, LAV) is a vaccine created by reducing the virulence of a pathogen, but still keeping it viable (or "live"). [1] Attenuation takes an infectious agent and alters it so that it becomes harmless or less virulent. [2] These vaccines contrast to those produced by "killing" the pathogen ...
An inactivated vaccine (or killed vaccine) is a type of vaccine that contains pathogens (such as virus or bacteria) that have been killed or rendered inactive, so they cannot replicate or cause disease. In contrast, live vaccines use pathogens that are still alive (but are almost always attenuated, that is, weakened).
It is impossible with other vaccine technologies such as inactivated vaccine (killed-virus vaccines), viral vector vaccine, RNA vaccines (that contain no virus), [14] or subunit vaccines (a vaccine technology using only isolated proteins of a virus). Only a small number of vaccines use technology that contain live virus which can theoretically ...
“Anytime these flu vaccines are being produced, they are – depending on which vaccines you are talking about – using live or attenuated virus, and you do have to grow it,” she said.
First generation vaccines are whole-organism vaccines – either live and weakened, or killed forms. [169] Live, attenuated vaccines, such as smallpox and polio vaccines, are able to induce killer T-cell (T C or CTL) responses, helper T-cell (T H) responses and antibody immunity.
Numerous observational studies and randomised trials (RCTs) have found that the impact on mortality of live and inactivated vaccines differ markedly. All live vaccines studied so far (BCG, measles vaccine, oral polio vaccine (OPV) and smallpox vaccine) have been shown to reduce mortality more than can be explained by prevention of the targeted infection(s).
Live attenuated influenza vaccine (LAIV) is a type of influenza vaccine in the form of a nasal spray that is recommended for the prevention of influenza. [ 2 ] [ 7 ] It is an attenuated live vaccine, unlike other influenza vaccines, which are inactivated vaccines .
Court documents show Jeffrey Burnham "wanted to confront" his brother "with the government poisoning people with COVID vaccines." He's also charged in two other deaths. Man killed pharmacist ...