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Proteus syndrome causes an overgrowth of skin, bones, muscles, fatty tissues, and blood and lymphatic vessels. Proteus syndrome is a progressive condition wherein children are usually born without any obvious deformities. Tumors of skin and bone growths appear as they age typically in early childhood. The musculoskeletal manifestations are ...
Children with some overgrowth syndromes such as Klippel–Trénaunay syndrome can be readily detectable at birth. [3] In contrast, other overgrowth syndromes such as Proteus syndrome usually present in the postnatal period, characteristically between the second and third year of life. [2]
Proteus penneri is a Gram-negative, facultatively anaerobic, rod-shaped bacterium. [1] It is an invasive pathogen [ 2 ] and a cause of nosocomial infections of the urinary tract or open wounds. [ 3 ]
Enterobacterales (of which Proteus is a member) and Pseudomonas species are the micro-organisms most commonly responsible for Gram-negative bacteremia and sepsis. The presence of the sepsis syndrome associated with a urinary tract infection (UTI) should raise the possibility of urinary tract obstruction. This is especially true of patients who ...
In 2006, some doctors diagnosed Sellars as having Proteus syndrome, a very rare condition thought to affect only 120 people worldwide, [1] but more recent diagnoses have focused on a PIK3CA gene mutation. Some reports still describe her condition as a rare form of Proteus syndrome, [2] but Sellars herself has disputed the diagnosis. [3]
Unlike the more commonly seen species of Proteus, P. hauseri is also able to convert tryptophan into indole, resulting in a positive indole test. P. hauser i shares a similar biochemical profile with Proteus vulgaris but can be differentiated by its ability to produce acid from trehalose.
Cohen was born in Boston, Massachusetts, and studied at the University of Michigan, Tufts University, the University of Minnesota, and Boston University.His post-graduate training included a fellowship in pathology and medical genetics with Robert Gorlin (1923–2006), an oral pathologist and geneticist who described a large number of syndromes, including one they delineated together known as ...
Proteus-like syndrome (PLS) is a condition similar to Proteus syndrome, but with an uncertain cause. [1] It's characterized by skeletal and hamartous overgrowth of multiple tissues, nevi in cerebriform connective tissue, blood vessel malformations and linear epidermal nevi.