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Mifepristone, and also known by its developmental code name RU-486, is a drug typically used in combination with misoprostol to bring about a medical abortion during pregnancy. [8] This combination is 97% effective [ 9 ] during the first 63 days (9 weeks) of pregnancy , yet effective in the second trimester as well.
The mifepristone-misoprostol combination is, by far, the most recommended drug regimen for medical abortions, but other drug combinations are available. Misoprostol alone, without mifepristone, may be used in some circumstances for medical abortion, and has even been demonstrated to be successful in the second trimester. [37]
In a medication abortion, a second drug, misoprostol, is taken within the next 24 to 48 hours. Misoprostol causes the uterus to contract, creating cramping and bleeding.
Mifepristone remains available in states where abortion is currently legal. Whether that will continue, though, is uncertain. Can you still get mifepristone and misoprostol for a medication abortion?
Aid Access is a nonprofit organization that provides access to medication abortion by mail to the United States and worldwide. It describes its work as a harm reduction strategy designed to provide safe access to mifepristone and misoprostol for those able to become pregnant in the United States who may not otherwise have access to abortion or miscarriage management services. [2]
Demand for the abortion pills mifepristone and misoprostol has grown as states have imposed bans or restrictions or seek to limit abortions after the reversal of Roe v. Wade in June 2022.
The American College of Obstetricians and Gynecologists says there is decades of evidence that mifepristone and misoprostol are safe and effective. The group cited a study showing that major adverse events such as significant infection and excessive blood loss occur in less than 0.32% of patients taking mifepristone for a medication abortion.
The court will consider whether the anti-abortion activists who sued the FDA to overturn its 2016 and 2021 approvals of mifepristone have the standing to do so, and whether the FDA’s actions are ...