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  2. D-dimer - Wikipedia

    en.wikipedia.org/wiki/D-dimer

    D-dimer (or D dimer) is a dimer that is a fibrin degradation product (FDP), a small protein fragment present in the blood after a blood clot is degraded by fibrinolysis. It is so named because it contains two D fragments of the fibrin protein joined by a cross-link , hence forming a protein dimer .

  3. Wells score (pulmonary embolism) - Wikipedia

    en.wikipedia.org/wiki/Wells_score_(pulmonary...

    The purpose of the rule is to select the best method of investigation (e.g. D-dimer testing, CT angiography) for ruling in or ruling out the diagnosis of PE, and to improve the interpretation and accuracy of subsequent testing, based on a Bayesian framework for the probability of the diagnosis.

  4. Pulmonary function testing - Wikipedia

    en.wikipedia.org/wiki/Pulmonary_function_testing

    Pulmonary function testing is a diagnostic and management tool used for a variety of reasons, such as: Diagnose lung disease. Monitor the effect of chronic diseases like asthma, chronic obstructive lung disease, or cystic fibrosis. Detect early changes in lung function. Identify narrowing in the airways. Evaluate airway bronchodilator reactivity.

  5. Pulmonary embolism - Wikipedia

    en.wikipedia.org/wiki/Pulmonary_embolism

    [13] [14] Diagnosis is based on signs and symptoms in combination with test results. [4] If the risk is low, a blood test known as a D-dimer may rule out the condition. [ 4 ] Otherwise, a CT pulmonary angiography , lung ventilation/perfusion scan , or ultrasound of the legs may confirm the diagnosis. [ 4 ]

  6. CT pulmonary angiogram - Wikipedia

    en.wikipedia.org/wiki/CT_pulmonary_angiogram

    [7] [8] Diagnostic algorithms for pulmonary embolism in pregnancy vary; however, a common compromise is to perform ultrasound testing for deep vein thrombosis of the legs, and if this is positive, make the diagnosis of pulmonary embolism on the basis of symptoms and presence of the DVT. CTPA would then only be performed if exhaustive non ...

  7. Fibrin degradation product - Wikipedia

    en.wikipedia.org/wiki/Fibrin_degradation_product

    If your body is unable to dissolve a clot, you may have abnormal levels of FDPs. The most notable subtype of fibrin degradation products is D-dimer. The levels of these FDPs rise after any thrombotic event. Fibrin and fibrinogen degradation product (FDP) testing is commonly used to diagnose disseminated intravascular coagulation. [2]

  8. Disseminated intravascular coagulation - Wikipedia

    en.wikipedia.org/wiki/Disseminated_intravascular...

    Diagnosis is typically based on blood tests. [2] Findings may include low platelets, low fibrinogen, high INR, or high D-dimer. [2] Treatment is mainly directed towards the underlying condition. [2] [3] Other measures may include giving platelets, cryoprecipitate, or fresh frozen plasma. [2] Evidence to support these treatments, however, is ...

  9. Cytokine release syndrome - Wikipedia

    en.wikipedia.org/wiki/Cytokine_release_syndrome

    The experimental drug TGN1412—also known as Theralizumab—caused extremely serious symptoms when given to six participants in a Phase I trial. [2] A controlled and limited CRS is triggered by active fever therapy with mixed bacterial vaccines (MBV) according to Coley; it is used for oncological and certain chronic diseases. [19]