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Epileptogenesis is the gradual process by which a typical brain develops epilepsy. [1] Epilepsy is a chronic condition in which seizures occur. [2] These changes to the brain occasionally cause neurons to fire in an abnormal, hypersynchronous manner, known as a seizure. [3]
Epileptogenesis may occur rapidly, further narrowing this window, but a delayed process known as "secondary epileptogenesis" can influence the progression and severity of epilepsy, offering opportunities for intervention even after its onset. Current research focuses on identifying methods and targets to prevent or slow epilepsy development.
Human infectious diseases may be characterized by their case fatality rate (CFR), the proportion of people diagnosed with a disease who die from it (cf. mortality rate).It should not be confused with the infection fatality rate (IFR), the estimated proportion of people infected by a disease-causing agent, including asymptomatic and undiagnosed infections, who die from the disease.
There are many causes of seizures. Organ failure, medication and medication withdrawal, cancer, imbalance of electrolytes, hypertensive encephalopathy , may be some of its potential causes. [ 2 ] The factors that lead to a seizure are often complex and it may not be possible to determine what causes a particular seizure, what causes it to ...
This process is known as epileptogenesis. [41] There is loss of inhibitory neurons because they die due to the injury. [41] [40] The brain may also adapt and make new neuron connections that may be hyper-excitatory. [41] [40] Brief seizures, such as absence seizures lasting 5–10 seconds, do not cause observable brain damage. [42]
Sudden unexpected death in epilepsy (SUDEP) is a fatal complication of epilepsy. [1] It is defined as the sudden and unexpected, non-traumatic and non-drowning death of a person with epilepsy, without a toxicological or anatomical cause of death detected during the post-mortem examination.
Vital statistics generally distinguish specific injuries and diseases as cause of death, from general categories like homicide, accident, and death by natural causes as manner of death. Both are listed in this category, as are both proximal and root causes of death. An injury that could be fatal is called major trauma; see also Category:Injuries.
In law, medicine, and statistics, cause of death is an official determination of the conditions resulting in a human's death, which may be recorded on a death certificate. A cause of death is determined by a medical examiner. In rare cases, an autopsy needs to be performed by a pathologist. The cause of death is a specific disease or injury, in ...