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2. Weight Loss Injections: What You Need to Know, From ... - AOL

   www.aol.com/weight-loss-injections-know-costs...

   Most type 2 diabetes injections for weight loss are glucagon-like peptide-1 (GLP-1) receptor agonists. These drugs mimic the GLP-1 hormone, which is made in your gastrointestinal tract when you ...

3. What Are Compounded GLP-1 Medications for Weight Loss? - AOL

   www.aol.com/compounded-glp-1-medications-weight...

   This is where compounded GLP-1 drugs come in. Due to the increase in demand, there are currently shortages of GLP-1 medications like semaglutide, tirzepatide , and liraglutide.

4. GLP1 poly-agonist peptides - Wikipedia

   en.wikipedia.org/wiki/GLP1_poly-agonist_peptides

   Tirzepatide, a dual agonist of GLP-1 and GIP receptors, is approved for type 2 diabetes and obesity. With an average 20 percent weight loss at a high dosage, it appears to be more effective than GLP-1 mono agonists although there have been no head to head trials as of 2023. [1] [3]

5. There’s still no generic Ozempic, but a lower-priced daily ...

   www.aol.com/news/still-no-generic-ozempic-lower...

   The US Food and Drug Administration on Monday approved a generic version of the daily injectable GLP-1 medicine liraglutide for people with type 2 diabetes, opening the door for lower-priced ...

6. GLP-1 receptor agonist - Wikipedia

   en.wikipedia.org/wiki/GLP-1_receptor_agonist

   Native GLP-1 is a peptide hormone with a half-life of two minutes because it is rapidly cleared by the enzyme dipeptidyl peptidase-4. [29] As a result, different GLP-1 agonist drugs are modified in various ways to extend the half-life, resulting in drugs that can be dosed multiple times per day, daily, weekly, or less often. [29]

7. Tirzepatide - Wikipedia

   en.wikipedia.org/wiki/Tirzepatide

   Tirzepatide has a greater affinity to GIP receptors than to GLP-1 receptors, and this dual agonist behavior has been shown to produce greater reductions of hyperglycemia compared to a selective GLP-1 receptor agonist. [14] Signaling studies reported that tirzepatide mimics the actions of natural GIP at the GIP receptor. [35]