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A diagram explaining factors affecting arterial pressure. Pathophysiology is a study which explains the function of the body as it relates to diseases and conditions. The pathophysiology of hypertension is an area which attempts to explain mechanistically the causes of hypertension, which is a chronic disease characterized by elevation of blood pressure.
Portal hypertension is a condition in which the blood pressure of the portal venous system is too high. It is often the result of cirrhosis of the liver. Liver cirrhosis can lead to increased intrahepatic vascular resistance and vasodilation of portal system arteries, both of which increase pressure in the portal vein. [4]
The portal vein and its branches supply most of the blood and nutrients from the intestine to the liver. [ 6 ] Cirrhosis (a form of chronic liver failure) is the most common cause of portal hypertension; other, less frequent causes are therefore grouped as non-cirrhotic portal hypertension .
Liver cancer. High blood pressure. Type 2 diabetes. Cardiovascular disease. Metabolic syndrome. Dyslipidemia (abnormal levels of lipids, or fats, in your blood) ... If you get a liver function ...
Liver damage has also been attributed to heroin usage over an extended period of time as well. [20] MASH has several causes, including obesity, high blood pressure, abnormal levels of cholesterol, type 2 diabetes, and metabolic syndrome. [21]
An important example of such a condition is elevated blood pressure in the portal vein. This condition, called portal hypertension , is a major complication of cirrhosis . In abdominal obesity fats, inflammatory cytokines and other toxic substances are transported by the portal vein from visceral fat into the liver, leading to hepatic insulin ...