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Historically, symptoms resembling FPIES were first reported in the 1960s, but awareness of the disease was limited for decades after. More recently, awareness has increased with establishment of an ICD-10 code in 2016, and the publication of the first international consensus guidelines for FPIES diagnosis by the American Academy of Allergy, Asthma, and Immunology in 2017.
Different underlying brain dysfunctions have been hypothesized to result in the common symptoms of autism, just as completely different brain types result in intellectual disability. [1] [5] In recent years, the prevalence and number of people diagnosed with the disorder have increased dramatically. There are many potential reasons for this ...
The autism spectrum may comprise a small set of disorders that converge on a few common molecular pathways, or it may be a large set of disorders with diverse mechanisms. [16] Autism appears to result from developmental factors that affect many or all functional brain systems. [17]
It was presumed initially that there was a common cause at the genetic, cognitive, and neural levels for classic autism's characteristic triad of symptoms. [34] However, over time, there was increasing evidence that autism was instead a complex and highly heritable disorder whose core aspects have distinct causes which often co-occur.
Pervasive developmental disorder not otherwise specified (PDD-NOS), which includes atypical autism, and is the most common (47% of autism diagnoses); [10] Typical autism, the best-known; Asperger syndrome (9% of autism diagnoses); Rett syndrome; and; Childhood disintegrative disorder (CDD). The first three of these disorders are commonly called ...
A 2006 review questioned the common assumption that most children with autism have an intellectual disability. [51] It is possible that the association between an intellectual disability and autism is not because they usually have common causes, but because the presence of both makes it more likely that both will be diagnosed. [52]
Autism Speaks – the world's largest autism advocacy organization that sponsors autism research and conducts awareness and outreach activities aimed at families, governments, and the public; some have argued that it is exploitative and unkind. Gluten-free, casein-free diet – diet that eliminates dietary intake of gluten and casein.
PDD-NOS is not a current part of the Diagnostic and Statistical Manual of Mental Disorders typology (as of the DSM-5), which is the most common diagnostic typology used in the United States. In the still used (though deprecated) ICD-10, it is considered "atypical autism" and "pervasive developmental disorder, unspecified". [8]