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The heart muscle may become inflamed in a condition called myocarditis, [46] most commonly caused by a viral infection [47] but sometimes caused by the body's own immune system. [48] Heart muscle can also be damaged by drugs such as alcohol, long standing high blood pressure or hypertension, or persistent abnormal heart racing. [49]
In a healthy heart all activities and rests during each individual cardiac cycle, or heartbeat, are initiated and orchestrated by signals of the heart's electrical conduction system, which is the "wiring" of the heart that carries electrical impulses throughout the body of cardiomyocytes, the specialized muscle cells of the heart.
As with skeletal muscles the heart can increase in size and efficiency with exercise. [1] Thus endurance athletes such as marathon runners may have a heart that has hypertrophied by up to 40%. [ 3 ] : 1063–64 The difference between maximum and minimum cardiac outputs is known as the cardiac reserve and this measures the residual capacity to ...
The conduction system consists of specialized heart muscle cells, situated within the myocardium. [3] There is a skeleton of fibrous tissue that surrounds the conduction system which can be seen on an ECG. Dysfunction of the conduction system can cause irregular heart rhythms including rhythms that are too fast or too slow.
An increase in sympathetic stimulation to the heart increases contractility and heart rate. An increase in contractility tends to increase stroke volume and thus a secondary increase in preload. An increase in preload results in an increased force of contraction by Starling's law of the heart; this does not require a change in contractility.
When this happens, the heart's atrioventricular node or bundle of His can take over as the pacemaker, starting the electrical signal that causes the heart to beat. [ 1 ] [ 5 ] Depending on where the rhythm originates in the AV node, the atria can contract before ventricular contraction due to retrograde conduction , during ventricular ...
In other words, there are two waves in the JVP for each contraction-relaxation cycle by the heart. The first beat represents that atrial contraction (termed a) and second beat represents venous filling of the right atrium against a closed tricuspid valve (termed v) and not the commonly mistaken 'ventricular contraction'. These wave forms may be ...
The action potential passes along the cell membrane causing the cell to contract, therefore the activity of the sinoatrial node results in a resting heart rate of roughly 60–100 beats per minute. All cardiac muscle cells are electrically linked to one another, by intercalated discs which allow the action potential to pass from one cell to the ...