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  2. RNA - Wikipedia

    en.wikipedia.org/wiki/RNA

    Unlike double-stranded DNA, RNA is usually a single-stranded molecule (ssRNA) [4] in many of its biological roles and consists of much shorter chains of nucleotides. [5] However, double-stranded RNA (dsRNA) can form and (moreover) a single RNA molecule can, by complementary base pairing, form intrastrand double helixes, as in tRNA.

  3. RNA virus - Wikipedia

    en.wikipedia.org/wiki/RNA_virus

    This is the single largest group of RNA viruses [23] and has been organized by the ICTV into the phyla Kitrinoviricota, Lenarviricota, and Pisuviricota in the kingdom Orthornavirae and realm Riboviria. [24] Positive-strand RNA viruses can also be classified based on the RNA-dependent RNA polymerase. Three groups have been recognised: [25]

  4. Nucleic acid - Wikipedia

    en.wikipedia.org/wiki/Nucleic_acid

    In most cases, naturally occurring DNA molecules are double-stranded and RNA molecules are single-stranded. [19] There are numerous exceptions, however—some viruses have genomes made of double-stranded RNA and other viruses have single-stranded DNA genomes, [20] and, in some circumstances, nucleic acid structures with three or four strands ...

  5. Nucleic acid structure - Wikipedia

    en.wikipedia.org/wiki/Nucleic_acid_structure

    Double-stranded RNA forms an A-type helical structure, unlike the common B-type conformation taken by double-stranded DNA molecules. The secondary structure of RNA consists of a single polynucleotide. Base pairing in RNA occurs when RNA folds between complementarity regions. Both single- and double-stranded regions are often found in RNA molecules.

  6. Positive-strand RNA virus - Wikipedia

    en.wikipedia.org/wiki/Positive-strand_RNA_virus

    Positive-strand RNA viruses (+ssRNA viruses) are a group of related viruses that have positive-sense, single-stranded genomes made of ribonucleic acid. The positive-sense genome can act as messenger RNA (mRNA) and can be directly translated into viral proteins by the host cell's ribosomes .

  7. Directionality (molecular biology) - Wikipedia

    en.wikipedia.org/wiki/Directionality_(molecular...

    Directionality, in molecular biology and biochemistry, is the end-to-end chemical orientation of a single strand of nucleic acid. In a single strand of DNA or RNA, the chemical convention of naming carbon atoms in the nucleotide pentose-sugar-ring means that there will be a 5′ end (usually pronounced "five-prime end"), which frequently ...

  8. Oligonucleotide - Wikipedia

    en.wikipedia.org/wiki/Oligonucleotide

    Oligonucleotides are short DNA or RNA molecules, oligomers, that have a wide range of applications in genetic testing, research, and forensics.Commonly made in the laboratory by solid-phase chemical synthesis, [1] these small fragments of nucleic acids can be manufactured as single-stranded molecules with any user-specified sequence, and so are vital for artificial gene synthesis, polymerase ...

  9. Transcription (biology) - Wikipedia

    en.wikipedia.org/wiki/Transcription_(biology)

    RNA polymerase, assisted by one or more general transcription factors, then unwinds approximately 14 base pairs of DNA to form an RNA polymerase-promoter open complex. In the open complex, the promoter DNA is partly unwound and single-stranded. The exposed, single-stranded DNA is referred to as the "transcription bubble". [6]