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Colchicine is taken by mouth. [11] The injectable route of administration for colchicine can be toxic. In 2008, the US Food and Drug Administration removed all injectable colchicine from the US market. [12] [13] Colchicine has a narrow therapeutic index, so overdosing is a significant risk.
It should be considered in all patients with acute pericarditis, preferably in combination with a short-course of NSAIDs. [10] For patients with a first episode of acute idiopathic or viral pericarditis, they should be treated with an NSAID plus colchicine 1–2 mg on first day followed by 0.5 daily or twice daily for three months.
Macrolides, including azithromycin, should not be taken with colchicine as it may lead to colchicine toxicity. Symptoms of colchicine toxicity include gastrointestinal upset, fever, myalgia, pancytopenia, and organ failure. [33] [34]
Taking certain types of medications can contribute to gout. A couple examples include cyclosporine, an immunosuppressant drug, and diuretics. ... Colchicine, a prescription medication that can ...
Colchicine. Limited research has shown that the anti-inflammatory drug colchicine may help stabilize Peyronie’s disease when combined with vitamin E in the early stages of the disease. The best ...
Colchicine (Colcrys) for pericarditis: colchicine is indicated for the treatment and prevention of gout, though it is also generally considered first-line treatment for acute pericarditis, as well as preventing recurrent episodes. Although the exact mechanism of colchicine is not fully understood, its anti-inflammatory effect for pericarditis ...