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NADPH is used as a reducing agent in many anabolic reactions. Proton translocating NAD(P) + transhydrogenase is one of the main ways that cells can regenerate NADPH after it is used. In E. coli, this pathway contribute equal amounts of NADPH as the pentose phosphate pathway, and both were the main producers of NADPH under standard growth ...
In biochemistry, NAD(P) + transhydrogenase (Si-specific) (EC 1.6.1.1) is an enzyme that catalyzes the chemical reaction. NADPH + NAD + NADP + + NADH. Thus, the two substrates of this enzyme are NADPH and NAD +, whereas its two products are NADP + and NADH. This enzyme participates in nicotinate and nicotinamide metabolism.
NAD(P) transhydrogenase, mitochondrial is an enzyme that in humans is encoded by the NNT gene on chromosome 5. [5] [6] [7] The NNT gene contains 26 exons and encodes a transhydrogenase protein that is ~109 kDa in molecular weight and is involved in antioxidant defense in the mitochondria. Two alternatively spliced variants, encoding the same ...
Hannah Storm. Jose Perez/Bauer-Griffin/GC Images Hannah Storm is opening up about her breast cancer diagnosis for the very first time. After undergoing a routine mammogram in November 2023 ...
Transhydrogenase may stand for NAD(P)+ transhydrogenase (Re/Si-specific) NAD(P)+ transhydrogenase (Si-specific) Proton-Translocating NAD(P)+ Transhydrogenase; Hydroxyacid-oxoacid transhydrogenase; Glutathione—cystine transhydrogenase; Lactate—malate transhydrogenase; Glutathione—homocystine transhydrogenase; Glutathione—CoA-glutathione ...
MCF-7 is a breast cancer cell line isolated in 1970 from a 69-year-old White woman. [1] MCF-7 is the acronym of Michigan Cancer Foundation-7, referring to the institute in Detroit where the cell line was established in 1973 by Herbert Soule and co-workers. [2] The Michigan Cancer Foundation is now known as the Barbara Ann Karmanos Cancer ...
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