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Having its own blood supply, Meckel's diverticulum is susceptible to obstruction or infection. Meckel's diverticulum is located in the distal ileum, usually within 60–100 cm (2 feet) of the ileocecal valve. This blind segment or small pouch is about 3–6 cm (2 inch) long and may have a greater lumen diameter than that of the ileum. [20]
This process creates the twisted shape of the large intestine. [6] In the fetus the ileum is connected to the navel by the vitelline duct. In roughly 2−4% of humans, this duct fails to close during the first seven weeks after birth, leaving a remnant called Meckel's diverticulum. [7]
The narrow mesentery predisposes some cases of malrotation to midgut volvulus, a twisting of the entire small bowel that can obstruct the mesenteric blood vessels leading to intestinal ischemia, necrosis, and death if not promptly treated. The fibrous Ladd's bands can constrict the duodenum, leading to intestinal obstruction.
A diverticulum of Kommerell is an outpouching (aneurysm) of the aorta where an aberrant right subclavian artery is located. [16] It is unusual nomenclature, in that focal dilatations of a blood vessel are properly referred to as aneurysms. Cardiac diverticulum is a very rare congenital malformation of the heart that is usually benign. [17]
Meckel's diverticulum – an out-pouching of the ileum, part of the small intestine, and found in approximately 2% of the population. Meckel's cartilage – A cartilaginous bar from which the mandible is formed. Described in 1820. A syndrome – Meckel syndrome – is also named after him. This condition was described in 1822.
A spotted gar larva at 22 days stained for cartilage (blue) and bone (red). Chondrogenesis is the biological process through which cartilage tissue is formed and developed. . This intricate and tightly regulated cellular differentiation pathway plays a crucial role in skeletal development, as cartilage serves as a fundamental component of the embryonic skele
The two can be differentiated as follows: a hamartoma is disorganized overgrowth of tissues in their normal location (e.g., Peutz–Jeghers polyps), while a choristoma is normal tissue growth in an abnormal location (e.g., osseous choristoma, [6] gastric tissue located in distal ileum in Meckel diverticulum).
Meckel's diverticulum; Appendix of the epididymis, a detached efferent duct of the epididymis; Appendix testis, a vestigial remnant of the Müllerian duct; Epiploic appendix, one of several small pouches of fat on the peritoneum along the colon and rectum Appendix of the laryngeal ventricle, a sac that extends from the laryngeal ventricle