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Oversaturation of urine with crystals is by far the biggest factor in stone formation in dogs and cats. [3] This oversaturation can be caused by increased excretion of crystals by the kidneys, water reabsorption by the renal tubules resulting in concentration of the urine, and changes in urine pH that influence crystallization.
Whereas primary feline urinary tract infections are rare in younger male cats, when a cat suffers an obstructive episode of FIC which has involved catheterisation and/or the symptomatic presence of crystals, then a secondary urinary tract infection becomes more likely as a follow-on complication. [35]
Dorsch R, Teichmann-Knorrn S, Sjetne Lund H. Urinary tract infection and subclinical bacteriuria in cats: A clinical update. J Feline Med Surg. 2019 Nov;21(11):1023-1038. doi: 10.1177 ...
Feline lower urinary tract disease (FLUTD) is a generic category term to describe any disorder affecting the bladder or urethra of cats. [1] It encompasses around 10 different diseases of the lower urinary tract, all of which can present with very similar symptoms: [2] frequent urination ; blood in urine
[10] [11] Struvite is the most common mineral found in urinary tract stones in dogs, [13] and is found also in urinary tract stones of cats and humans. Struvite stones are potentiated by bacterial infection that hydrolyzes urea to ammonium and raises urine pH to neutral or alkaline values.
Prerenal causes in cats are mainly blood loss, dehydration, shock, congestive heart failure, hyperthyroidism, but also fever or severe physical exertion. Possible postrenal causes include obstruction of the urinary tract due to bladder stones or tumors, tears of the urinary bladder, ureter, or urethra. [26]
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