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  2. Do Any of These 6 Popular Over-the-Counter Antidepressants ...

    www.aol.com/lifestyle/6-popular-over-counter...

    For others with more mild depression or moderate symptoms of depression, over-the-counter medication ... prescription medications and active ingredients vary among brands and individual batches ...

  3. Breakthrough antidepressants with fewer side effects could ...

    www.aol.com/finance/breakthrough-antidepressants...

    The FDA approved Johnson & Johnson’s drug for treatment-resistant depression in 2019. ... like the venerable cough suppressant dextromethorphan found in Robitussin and other over-the-counter ...

  4. Dextromethorphan/bupropion - Wikipedia

    en.wikipedia.org/wiki/Dextromethorphan/bupropion

    The elimination half-lives of bupropion active metabolites are 35 hours for hydroxybupropion, 44 hours for erythrohydrobupropion, and 33 hours for threohydrobupropion. [1] Bupropion inhibits the metabolism of dextromethorphan by inhibiting the enzyme CYP2D6, the major enzyme responsible for the metabolism of dextromethorphan. [1]

  5. Dextromethorphan - Wikipedia

    en.wikipedia.org/wiki/Dextromethorphan

    Dextromethorphan, sold under the brand name Robitussin among others, is a cough suppressant used in many cough and cold medicines. [6] In 2022, the US Food and Drug Administration (FDA) approved the combination dextromethorphan/bupropion to serve as a rapid-acting antidepressant in people with major depressive disorder.

  6. Your Guide to the 6 Most Common Types of Depression Medications

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    Medications for Depression: An Overview. Antidepressants are a class of medications used very commonly to treat depression. In fact, nearly 13 percent of people 12 and over in the U.S. used ...

  7. Nortriptyline - Wikipedia

    en.wikipedia.org/wiki/Nortriptyline

    Nortriptyline is an active metabolite of amitriptyline by demethylation in the liver. Chemically, it is a secondary amine dibenzocycloheptene and pharmacologically it is classed as a first-generation antidepressant. [36] Nortriptyline may also have a sleep-improving effect due to antagonism of the H 1 and 5-HT 2A receptors. [37]

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