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The SPARTAC trial compared 48 weeks of ART vs 12 weeks vs no treatment in acute HIV infection and found that 48 weeks of treatment delayed the time to decline in CD4 count below 350 cells per ml by 65 weeks and kept viral loads significantly lower even after treatment was stopped. [58]
The treatment consists of a series of injections of rabies vaccine and immunoglobulin. [10] Rabies vaccine is given to both humans and animals who have been potentially exposed to rabies. [11] As of 2018, the average estimated cost of rabies post-exposure prophylaxis was US$ 108 (along with travel costs and loss of income). [12]
In 2023, 630,000 people died from HIV-related causes, an estimated 1.3 million people acquired HIV and about 39.9 million people worldwide living with HIV, 65% of whom are in the World Health Organization (WHO) African Region. [5] [7] HIV/AIDS is considered a pandemic—a disease outbreak which is present over a large area and is actively ...
Strong sales of medicines for HIV, the virus that causes AIDS, were one of the drivers behind the company's performance last year, generating 6.44 billion pounds ($8.13 billion) in annual sales.
Raltegravir, sold under the brand name Isentress, is an antiretroviral medication used, together with other medication, to treat HIV/AIDS. [5] It may also be used, as part of post exposure prophylaxis, to prevent HIV infection following potential exposure. [6] It is taken by mouth. [5]
Emtricitabine/tenofovir is also used for HIV post-exposure prophylaxis. People who start taking emtricitabine/tenofovir see HIV reduction benefits up to 72 hours after starting, but the medicine must be taken for thirty days after a high-risk sexual event to ensure HIV transmission levels are optimally reduced. [21] [22]
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