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The elimination half-life of testosterone varies depending on the route of administration and formulation and on whether or not it is esterified. [8] The elimination half-life of testosterone in the blood or by intravenous injection is only about 10 minutes.
For reference, testosterone enanthate has an elimination half-life of 4.5 days and a mean residence time of 8.5 days and requires frequent administration of approximately once per week. [21] Large fluctuations in testosterone levels result with it, with levels initially being elevated and supraphysiological. [21]
Testosterone propionate is administered in oil via intramuscular injection. [1] [2] It has a relatively short elimination half-life and mean residence time of 2 days and 4 days, respectively. [1] [2] As such, it has a short duration of action and must be administered two to three times per week. [16]
Testosterone undecanoate has a very long elimination half-life and mean residence time when given as a depot intramuscular injection. [27] [7] [8] Its elimination half-life is 20.9 days and its mean residence time is 34.9 days in tea seed oil, while its elimination half-life is 33.9 days and its mean residence time is 36.0 days in castor oil.
Testosterone. Even the word alone sounds manly. For men, testosterone is important for drive, fertility, heart health, bone health, energy and mood — to name just a few benefits.
Pharmacokinetics of testosterone esters Testosterone ester Form Route T max Tooltip Time to peak levels t 1/2 Tooltip Elimination half-life MRT Tooltip Mean residence time; Testosterone undecanoate: Oil-filled capsules: Oral? 1.6 hours: 3.7 hours Testosterone propionate: Oil solution: Intramuscular injection? 0.8 days: 1.5 days Testosterone ...
WASHINGTON (AP) - A consumer advocacy group is calling on the Food and Drug Administration to add a bold warning label to popular testosterone drugs for men in light of growing evidence that the ...
Testosterone enanthate has an elimination half-life of 4.5 days and a mean residence time of 8.5 days when used as a depot intramuscular injection. [2] It requires frequent administration of approximately once per week, and large fluctuations in testosterone levels result with it, with levels initially being elevated and supraphysiological. [2]
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