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Baclofen, sold under the brand name Lioresal among others, is a medication used to treat muscle spasticity, such as from a spinal cord injury or multiple sclerosis. [ 8 ] [ 9 ] It may also be used for hiccups and muscle spasms near the end of life, [ 9 ] and off-label to treat alcohol use disorder [ 10 ] [ 11 ] or opioid withdrawal symptoms. [ 12 ]
In fact, recent research estimates 40% of girls and young women aged 12 to 21 in the US are affected by iron deficiency, with menstruation listed as the primary risk factor. Pregnancy and ...
[69] [70] Baclofen withdrawal can be more intense if it is administered intrathecally or for long periods of time. If baclofen or phenibut is used for long periods of time, it can resemble intense benzodiazepine, GHB, or alcohol withdrawal. To minimize withdrawal symptoms, baclofen or phenibut should be tapered down slowly.
Sleep inertia is a physiological state of impaired cognitive and sensory-motor performance that is present immediately after awakening. It persists during the transition of sleep to wakefulness, where an individual will experience feelings of drowsiness, disorientation and a decline in motor dexterity.
Muscle relaxation and paralysis can theoretically occur by interrupting function at several sites, including the central nervous system, myelinated somatic nerves, unmyelinated motor nerve terminals, nicotinic acetylcholine receptors, the motor end plate, and the muscle membrane or contractile apparatus.
The alleged mechanism for the feeling of a crash is correlated with an abnormally rapid rise in blood glucose after eating. This normally leads to insulin secretion (known as an insulin spike ), which in turn initiates rapid glucose uptake by tissues, either storing it as glycogen or fat , or using it for energy production.
Over half of Americans spend time on their phones within an hour of going to sleep, according to a survey by the National Sleep Foundation. The brain needs to wind down long before bedtime to get ...
Image credits: raka_defocus #3. I was studying with a friend in their dorm in college. It was a suited dorm with a shared bathroom. Heard multiple girls going into the bathroom together franticly ...