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Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the colon and small intestine, with Crohn's disease and ulcerative colitis (UC) being the principal types. [3] Crohn's disease affects the small intestine and large intestine, as well as the mouth, esophagus, stomach and the anus, whereas UC primarily affects the colon ...
Ulcerative colitis (UC) is one of the two types of inflammatory bowel disease (IBD), with the other type being Crohn's disease. [1] It is a long-term condition that results in inflammation and ulcers of the colon and rectum. [1] [7] The primary symptoms of active disease are abdominal pain and diarrhea mixed with blood (hematochezia). [1]
[22] [23] Inflammatory bowel disease resulted in 47,400 deaths in 2015, [24] and those with Crohn's disease have a slightly reduced life expectancy. [1] Onset of Crohn's disease tends to start in adolescence and young adulthood, though it can occur at any age. [25] [1] [3] [26] Males and females are affected roughly equally. [3]
The systemic use of corticosteroids in the context of inflammatory bowel disease can promote CMV infection in the colon. [1] The corticosteroids used as a primary treatment for flare-up events of inflammatory bowel disease reduce the autoimmune activity of the T lymphocytes and monocytes that contribute to the inflammation of the colon and small intestine.
Signs and symptoms of CDI range from mild diarrhea to severe life-threatening inflammation of the colon. [16]In adults, a clinical prediction rule found the best signs to be significant diarrhea ("new onset of more than three partially formed or watery stools per 24-hour period"), recent antibiotic exposure, abdominal pain, fever (up to 40.5 °C or 105 °F), and a distinctive foul odor to the ...
Ischemic bowel disease: This usually affects older people and can be due to blocked arteries. Microscopic colitis, a type of inflammatory bowel disease where changes are seen only on histological examination of colonic biopsies. Bile salt malabsorption (primary bile acid diarrhea) where excessive bile acids in the colon produce a secretory ...
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