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Proximal diabetic neuropathy, also known as diabetic amyotrophy, is a complication of diabetes mellitus that affects the nerves that supply the thighs, hips, buttocks and/or lower legs. Proximal diabetic neuropathy is a type of diabetic neuropathy characterized by muscle wasting, weakness, pain, or changes in sensation/numbness of the leg.
The common ages of occurrence happen between thirty and forty, and are scarcely found in patients younger than twenty; [70] this has been known to affect all lifestyles. [ 46 ] Piriformis syndrome is often left undiagnosed and mistaken with other pains due to similar symptoms with back pain , quadriceps pain, lower leg pain, and buttock pain.
Patients also frequently report persistent or intermittent pain or dysthesias in posterior hip, buttocks, or thigh. [4] Unlike discogenic sciatica (caused by the spine), patients with deep gluteal syndrome report exacerbation of symptoms with pressure in the buttocks, such as tenderness or pain on deep palpation, or pain on prolonged sitting.
Peripheral neuropathy may be classified according to the number and distribution of nerves affected (mononeuropathy, mononeuritis multiplex, or polyneuropathy), the type of nerve fiber predominantly affected (motor, sensory, autonomic), or the process affecting the nerves; e.g., inflammation (), compression (compression neuropathy), chemotherapy (chemotherapy-induced peripheral neuropathy).
Small fiber neuropathy is considered a form of peripheral neuropathy because it affects the peripheral nervous system, which connects the brain and spinal cord to muscles and to cells that detect sensations such as touch, smell, and pain. Insensitivity to pain can be particularly problematic.
Weakness or paralysis of these muscles caused by a damaged superior gluteal nerve can result in a weak abduction in the affected hip joint. This gait disturbance is known as Trendelenburg gait. In a positive Trendelenburg's sign the pelvis sags toward the normal unsupported side (the swing leg).