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Stercoral ulcer is an ulcer of the colon due to pressure and irritation resulting from severe, prolonged constipation due to a large bowel obstruction, damage to the autonomic nervous system, or stercoral colitis. It is most commonly located in the sigmoid colon and rectum.
The anti-TNF-α monoclonal antibody infliximab is a major biological therapy for inflammatory bowel diseaseBiological therapy, the use of medications called biopharmaceuticals or biologics that are tailored to specifically target an immune or genetic mediator of disease, plays a major role in the treatment of inflammatory bowel disease. [1]
A human colon is considered abnormally enlarged if it has a diameter greater than 12 cm [3] in the cecum (it is usually less than 9 cm [4]), greater than 6.5 cm [3] in the rectosigmoid region and greater than 8 cm [3] for the ascending colon. The transverse colon is usually less than 6 cm in diameter. [4] A megacolon can be either acute or ...
While it will take some time and more research, doctors may eventually use tulisokibart in clinical practice to help treat moderate to severe ulcerative colitis. “This was a phase 2 study.
Ulcerative colitis is a type of inflammatory bowel disease (IBD). [4] It is a long-term condition that results in inflammation and ulcers of the colon and rectum. [4] [5] The primary symptoms of active disease are abdominal pain and diarrhea mixed with blood (hematochezia). Weight loss, fever, and anemia may also occur. Often, symptoms come on ...
Physicians first direct treatment to inducing a remission which involves relief of symptoms and mucosal healing of the lining of the colon and then longer-term treatment to maintain the remission. Anaemia , caused by both chronic blood loss from the gastrointestinal tract and reduced absorption due to the up-regulation of hepcidin should also ...
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