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Sepsis is a potentially life-threatening condition that arises when the body's response to infection causes injury to its own tissues and organs. [4] [7] This initial stage of sepsis is followed by suppression of the immune system. [8] Common signs and symptoms include fever, increased heart rate, increased breathing rate, and confusion. [1]
Septic shock is a result of a systemic response to infection or multiple infectious causes. The precipitating infections that may lead to septic shock if severe enough include but are not limited to appendicitis, pneumonia, bacteremia, diverticulitis, pyelonephritis, meningitis, pancreatitis, necrotizing fasciitis, MRSA and mesenteric ischemia.
EOS refers to sepsis presenting in the first 7 days of life (although some refer to EOS as within the first 72 hours of life), with LOS referring to presentation of sepsis after 7 days (or 72 hours, depending on the system used). Neonatal sepsis is the single most common cause of neonatal death in hospital as well as community in developing ...
Early-onset sepsis (EOS), defined as onset of symptoms within 72 hours of life, is generally caused by transmission of pathogens from the female genitourinary system to the fetus. Pathogens can infect the fetus via vertical transmission (direct transmission through the placenta in utero) or infection during delivery as fetus passes through ...
Severe sepsis, is sepsis that is causing poor organ function, or insufficient blood flow to the body. [4] Insufficient blood flow can manifest as either low blood pressure, high blood lactate, or low urine output. [4]
Septic thrombophlebitis is characterized by a bacterial or fungal infection that coexists with venous thrombosis.Deep veins or superficial veins could be affected. Septic thrombophlebitis can manifest as anything from a harmless condition that affects a small area of superficial veins to serious systemic infections that cause shock and even death.
Bacteremia can have several important health consequences. Immune responses to the bacteria can cause sepsis and septic shock, which, particularly if severe sepsis and then septic shock occurs, have high mortality rates, especially if not treated quickly (though, if treated early, currently mild sepsis can usually be dealt with successfully). [6]
Overwhelming post-splenectomy sepsis (OPSS) [1] Specialty: Infectious disease: Usual onset: 24–48 hours following presentation with mild viral symptoms [2] Causes: Exposure to pathogens following splenectomy or asplenia: Risk factors: Splenectomy in the past 2–3 years, removal of spleen for hematological reasons, being under the age of 2 [2 ...