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Hypervitaminosis A refers to the toxic effects of ingesting too much preformed vitamin A (retinyl esters, retinol, and retinal). Symptoms arise as a result of altered bone metabolism and altered metabolism of other fat-soluble vitamins. Hypervitaminosis A is believed to have occurred in early humans, and the problem has persisted throughout ...
Retinol. This is an over-the-counter retinoid derived from vitamin A — and it’s much less potent than prescription tretinoin. ... Side effects include minor pain, swelling, and bruises at the ...
Some people fear the side effects of retinol, but experts say to stick it out for the best results. Read on for everything there is to know about retinol purging. Just Started Using Retinol?
Toxic effects of retinoids occur with both acute or prolonged intake, depending on which retinoid is considered. The specific toxicity is related to the mechanism of action as well as exposure. A medical sign of chronic or acute poisoning with retinol is hypervitaminosis A, which includes the presence of painful tender swellings on the long bones.
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A high capacity for long-term storage of retinol means that well-nourished humans can go months on a vitamin A-deficient diet, while maintaining blood levels in the normal range. [4] Only when the liver stores are nearly depleted will signs and symptoms of deficiency show. [4]