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However, not all of them are safe to use during pregnancy. One of the components of bismuth subsalicylate is salicylate, which is a component that crosses the placenta. Due to this, there is an increased risk for intrauterine growth retardation, fetal hemorrhage, and maternal hemorrhage within organogenesis and in the second/third trimester. [ 12 ]
Blood calcium levels should be measured when used and extra care should be taken in those with a history of kidney stones. [3] At normal doses, use is regarded as safe in pregnancy and breastfeeding. [1] [4] Calcium gluconate is made by mixing gluconic acid with calcium carbonate or calcium hydroxide. [5]
There is no clear first-line tocolytic agent. [6] [7] Current evidence suggests that first line treatment with β 2 agonists, calcium channel blockers, or NSAIDs to prolong pregnancy for up to 48 hours is the best course of action to allow time for glucocorticoid administration.
Calcium carbonate is the active ingredient in agricultural lime and is produced when calcium ions in hard water react with carbonate ions to form limescale. It has medical use as a calcium supplement or as an antacid , but excessive consumption can be hazardous and cause hypercalcemia and digestive issues.
While some studies recommend the administration of certain agents, others underline the possible adverse effects on fetal development. In general, a-methyldopa, β-blockers and calcium channel blockers are the first or second treatment line for hypertension during pregnancy.
Calcium lactate has similar absorption as calcium carbonate, [42] but is more expensive. [41] [26] Unlike calcium carbonate, calcium lactate can be absorbed at various pHs, thus it does not need to be taken with food. [26] Calcium lactate is a less concentrated forms of calcium than calcium carbonate. [41] Calcium lactate contains 13% elemental ...
Hypocalcemia (decreased calcium levels) is a contraindication to the use of cinacalcet. Those who have serum calcium levels less than 7.5 mg/dL should not be started on cinacalcet. Hypocalcemia symptoms include paresthesias, myalgias, muscle cramping, tetany, and convulsions.
Calcium acetate and magnesium carbonate compounds bind phosphorus derived from food thereby forming indigestible phosphate salts in the intestine that are subsequently excreted with the faeces. The aim of the therapy is to reach a normal serum phosphorus level, i.e. between 0.81 and 1.45 mmol/L (2.5–4.5 mg/dL).