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Naloxone was created in a laboratory, patented in 1961, and approved by the FDA a decade later. [1] It was first proposed in the 1990s for community-based provisions of take-home naloxone rescue kits (THN) to opioid users, which involved training opioid users, along with their family or friends, in awareness, emergency management, and administration of naloxone. [2]
Maternal use of opioids has become prolific. The use of opioids during pregnancy creates a dependency in the newborn who experiences withdrawal symptoms shown in clinical signs of opioid withdrawal. These signs are grouped as the neonatal opioid withdrawal syndrome, also known more broadly as neonatal abstinence syndrome. [33]
Drug detoxification (informally, detox) is variously construed or interpreted as a type of "medical" intervention or technique in regards to a physical dependence mediated by a drug; as well as the process and experience of a withdrawal syndrome or any of the treatments for acute drug overdose (toxidrome).
Quenton Erpenbeck used heroin for 16 months. For 13 of them he was trying to get off it, his mother, Ann, recalled. He did a 30-day, 12-step-based residential program and followed up with attending 90 AA or NA meetings in 90 days before relapsing. Toward the end of his life, he started taking Suboxone.
Drug withdrawal, drug withdrawal syndrome, or substance withdrawal syndrome [1] is the group of symptoms that occur upon the abrupt discontinuation or decrease in the intake of pharmaceutical or recreational drugs.
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One way to explain the stubbornness of the epidemic is to look at the availability of the maintenance medication buprenorphine, sold most commonly under the brand name Suboxone. Taking the medication (or methadone), along with counseling, is an opioid addict’s best chance for recovery, public health experts say.
As the opioid epidemic continues raging, some advocates in Kentucky are pushing the state to explore a little-known psychedelic drug called ibogaine as a possible treatment option for addiction, a ...
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