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Donepezil, sold under the brand name Aricept among others, is a medication used to treat dementia of the Alzheimer's type. [3] [4] [8] It appears to result in a small benefit in mental function and ability to function. [9]
[4] [5] Side effects when used as drugs may include loss of appetite, nausea, vomiting, loose stools, vivid dreams at night, dehydration, rash, bradycardia, peptic ulcer disease, seizures, weight loss, rhinorrhea, salivation, muscle cramps, and fasciculations. [6] [7] ChEIs are indirect-acting parasympathomimetic drugs. [8]
Studies have shown that nicergoline also increases nerve growth factor in the aged brain. [9] [10] In addition to the α 1A-adrenergic receptor, nicergoline is an antagonist of the serotonin 5-HT 1A receptor (IC 50 = 6 nM) and shows moderate affinity for serotonin 5-HT 2 and α 2-adrenergic receptors and low affinity for the dopamine D 1 and D ...
These side effects arise in approximately 10–20% of users, are mild to moderate in severity, and can be managed by slowly adjusting medication doses. [190] Less common secondary effects include muscle cramps , decreased heart rate ( bradycardia ), decreased appetite and weight, and increased gastric acid production.
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Dementia is a devastating condition that impacts up to 10 percent of older adults. And while there's no cure, getting diagnosed early can help patients get on a treatment plan and families prepare ...
Serotonin syndrome (SS) is a group of symptoms that may occur with the use of certain serotonergic medications or drugs. [1] The symptoms can range from mild to severe, and are potentially fatal. [4] [5] [2] Symptoms in mild cases include high blood pressure and a fast heart rate; usually without a fever. [2]
Berberine can upset your gastrointestinal system, causing symptoms like: nausea, diarrhea, constipation, gas and abdominal pain, Simmons says. It’s also possible that taking berberine can ...